Analysis of Two Single and Three Double Long-Chain Quaternary Ammonium Compounds via Non-Aqueous Capillary Electrophoresis with Indirect Ultraviolet Detection

A novel method utilizing non-aqueous capillary electrophoresis (NACE) with indirect ultraviolet detection (IUD) has been developed for the analysis of five quaternary ammonium compounds (QACs). The QACs analyzed in this study include dodecyl trimethyl bromide, tetradecyl dioctyl dimethyl chloride, octyldecyl chloride and didecyl dimethy bromide. separation process was carried out on an uncoated fused quartz a total length 50.2 cm (effective 40.0 cm) diameter 50 μm. buffer consisted mixture MeOH/ACN (90:10, v/v) containing 2 mmol/L sodium acetate, trifluoroacetic acid (TFA) 16 benzyl chloride. sample utilized (20:80, TFA. During analysis, voltage 7 kV applied, resulting current approximately 2.3 μA. wavelength set at 214 nm to ensure optimal sensitivity. Under conditions, exhibited excellent performance characteristics, limit 0.5 mg/L quantitation 5.0 QACs. Linear calibration curves were obtained concentration range 100.0 mg/L, correlation coefficients exceeding 0.999 all compounds. recoveries ranged from 92.3% 114.7%, relative standard deviations below 7.4%. To assess applicability NACE-IUD method, 17 commercially available samples successfully analyzed. results confirmed suitability accurate determination disinfectant products. Notably, offers environmentally friendly approach these